Brussels, Belgium
June 26, 2023

Welcome to hubXchange’s Advanced Therapies Xchange Europe 2023, bringing together executives from pharma and biotech to address and find solutions to the key issues faced in cell and gene therapeutics.

Discussion topics will cover Cell Tx Development, Gene Tx Development, C&G Tx Bioprocessing and C&G Tx Manufacturing.

Take advantage of this unique highly interactive meeting format designed for maximum engagement, collaboration and networking with your peers.

Venue: DoubleTree by Hilton Brussels City, Ginestestraat 3 Rue Gineste, 1210 Brussels, Belgium


  • Enhancing CAR-T cell efficacy
  • Alternatives to autologous-allogenic and in vivo cell therapies
  • The promise and challenges of PSC-CAR-NK cell therapy
  • Tackling the challenges of AAV vector manufacturing
  • Adapting analytics and quality control in cell therapy manufacturing to ensure adequate safety, purity and potency of final products
  • Future of autologous cell therapy

Full Xchange Agenda

Click on each track for detailed agenda

Cell Tx Development

Titles and Bullets
08:00 – 08:30
08:30 – 09:00

Opening Address & Keynote Presentation ALBUMEDIX (Elm)

09:05 – 10:05

The promise and challenges of TCR-based cell therapies

  • Harnessing the immune system to defeat disease
  • Precision approaches to developing TCR-based cell therapies
  • Manufacture and commercialization of TCR-based cell therapies

Vice President, Business Development, Chief Development Officer, Anocca

Mark Farmery, PhD, is CDO at Anocca and has been with the company since 2020. He is an experienced biopharma/biotech strategic leader and business developer and is responsible for Anocca’s corporate development and building technology and manufacturing partnerships. Dr Farmery received his PhD from the University of Leeds, UK, and has previously held senior roles at Karolinska Institutet, Abliva and AstraZeneca.

Mark Farmery portrait
10:10 – 10:40
1-2-1 Meetings/Networking Break
10:40 – 11:10
1-2-1 Meetings / Networking Break
11:10 – 11:20
Morning Refreshments
11:20 – 12:20

Beyond development and into the clinic: How do we mitigate the impacts of the narrow cell viability window to make cell therapies viable at scale, as treatments in hospitals worldwide?

  • How to improve the viability of cell therapies post-cryopreservation
  • Important considerations for extending cell viability at room temperature – during transport, and importantly, in the clinic
  • How may the quality of excipients affect the performance of the final cell therapy product?


Director of Sales and Business Development, Europe, Albumedix

Paul is passionate about delivering new medicines and advanced therapies to market at pace using albumin-enabled solutions. Paul, and the team he manages, are responsible for developing partnerships that bring to reality albumin-enabled solutions that support advanced therapies from development to commercialisation.

Paul Heath
12:20 – 13:20

Networking Lunch

13:20 – 13:50

Spotlight Presentation

Generation of Recombinant Tool Antibodies to Support Cell and Gene Therapy Development

Highly specialized antibodies are required for cellular kinetics and bioanalytical assays supporting cell and gene therapy development. These antibodies are difficult to generate utilizing animal immunization, and are prone to variability between batches and inconsistent supply. Bio-Rad custom antibody experts have developed recombinant antibodies against chimeric antigen receptors and transgene products utilizing a process that combines antibody phage display with SpyTag technology. Applying these powerful technologies enables the production of antibodies in multiple formats in under 3 months and offers a range of options for site-directed conjugation. These highly specific, well-characterized antibody reagents are sequence defined, guaranteeing a secure supply throughout the assay lifecycle. Our scientists also offer therapeutic antibody discovery through the Pioneer Platform to unlock discovery of clinical-quality candidates on industry-leading timelines.

Technical Sales Specialist, Custom Antibodies, Bio-Rad.

Katharina Reefschläger is a technical sales specialist for Bio-Rad´s Custom Antibody
Generation Platforms. She has been with Bio-Rad in various sales related positions for over 10 years. Prior to this she worked in a genetic diagnostic lab as scientific
customer support for more than 2 years. Katharina holds a diploma in Biology from Julius-Maximilians-University Würzburg/Germany and a PhD in Biology from Ludwig-Maximilians-University Munich/Germany.

Katharina Reefschläger
13:55 – 14:25
1-2-1 Meetings / Networking Break
14:30 – 15:00

Spotlight Presentation

Building a Commercial-Ready Cell & Gene Therapy Supply Chain Key considerations in the assessment and integration of cGMP compliant ancillary materials for cell therapy manufacturing

PhD, Director of Business Development, Akron

Sara has more than a decade of research and business development experience in the Cell and Gene Therapy industry. After completing her PhD at Karolinska Institute (Sweden) in Regenerative Medicine, she joined the Japanese company Healios to manage the development of their overseas cell therapy projects. Her passion and extensive knowledge on ATMPs, GMP and scale-up manufacture has promoted Akron’s growth, expanding its presence and influence into Europe, bringing Akron’s products to more than 100 companies in the C&GT field.

sara padrell
15:00 – 16:00

Alternatives to autologous- allogenic and in vivo cell therapies

  • Why do we need an alternative to autologous products? Advantages and disadvantages of allogenic therapies
  • In vivo vs ex vivo: safety, delivery systems and ethical issues
  • Implications of the manufacturing of allogeneic products and in vivo therapies: donor choice, cell banks, cost reduction towards universal formulations

Science Strategy Associate Director, Quell Therapeutics

Maria Eugenia Alonso
16:00 – 17:30
Evening Drinks Reception


Advanced Therapies Xchange | Europe 2023